A chromenoquinoline-based fluorescent off–onthiol probe for bioimaging

KAND, DNYANESHWAR; Varma, Sreejith Jayasree; TALUKDAR, PINAKI; Kalle, Arunasree Marasanapalli

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A chromenoquinoline-based fluorescent off–onthiol probe for bioimaging

KAND, DNYANESHWAR; Kalle, Arunasree Marasanapalli; Varma, Sreejith Jayasree; TALUKDAR, PINAKI

URI: http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/3625 https://doi.org/10.1039/C2CC16593G Date: 2012-01

Abstract:

A new chromenoquinoline-based fluorescent off–onthiol probe 2 is reported. In aqueous buffer solutions at physiological pH, the probe exhibited 223-fold enhancement in fluorescence intensity by a Michael addition of cysteine to the maleimide appended to a chromenoquinoline. Cell permeability and live cell imaging of thiols are also demonstrated.

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