Gap junctions and excitation patterns in continuum models of islets

dc.contributor.author	GOEL, PRANAY	en_US
dc.contributor.author	Sneyd, James	en_US
dc.date.accessioned	2019-07-23T11:33:27Z
dc.date.available	2019-07-23T11:33:27Z
dc.date.issued	2012-09	en_US
dc.identifier.citation	Discrete and Continuous Dynamical Systems - Series B, 17(6), 1969-1990.	en_US
dc.identifier.issn	1531-3492	en_US
dc.identifier.issn	1553-524X	en_US
dc.identifier.uri	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/3734
dc.identifier.uri	https://doi.org/10.3934/dcdsb.2012.17.1969	en_US
dc.description.abstract	We extend the development of homogenized models for excitable tissues coupled through "doughball" gap junctions. The analysis admits nonlinear Fickian fluxes in rather general ways and includes, in particular, calcium-gated conductance. The theory is motivated by an attempt to understand wave propagation and failure observed in the pancreatic islets of Langerhans. We reexamine, numerically, the role that gap junctional strength is generally thought to play in pattern formation in continuum models of islets.	en_US
dc.language.iso	en	en_US
dc.publisher	American Institute of Mathematical Sciences	en_US
dc.subject	Gap junctions	en_US
dc.subject	Excitation patterns	en_US
dc.subject	Continuum models of islets	en_US
dc.subject	2012	en_US
dc.title	Gap junctions and excitation patterns in continuum models of islets	en_US
dc.type	Article	en_US
dc.contributor.department	Dept. of Mathematics	en_US
dc.identifier.sourcetitle	Discrete and Continuous Dynamical Systems - Series B	en_US
dc.publication.originofpublisher	Foreign	en_US