Theses submitted to IISER Pune in partial fulfilment of the requirements of the BS-MS dual degree and Ph.D programmes. Also, project reports submitted by the students.
Self-assembling cyclic peptides are important building blocks for constructing synthetic nanotubes. They can be primarily classified into D, L-cyclic peptides, cyclic β-peptides, cyclic α, γ-peptides, and cyclic peptides ...
The first-passage time of a stochastic time-series, defined to be the time taken by it to cross a predefined threshold for the first time, has a wide range of applications across disciplines. However, if the time-series ...
Heparan sulfate proteoglycans (HSPGs) are essential components of the extracellular matrix and cell surfaces, playing pivotal roles in various biological processes. Composed of a core protein with covalently attached heparan ...
In the evolving landscape of modern precision cosmology, the continuous progress of ongoing and upcoming surveys has provided us with an unprecedented level of statistical power or drawing robust inference. The study of ...
Let K = Q(
Ô≠d) where d(> 0) is a square-free integer. Let OK be the ring of integers
of K.
Consider the hyperbolic 3-space H3 ( Upper half space),
H3 := {(z, t) œ C ◊ R | t > 0}.
We define the extended 3- dimensional ...
As the early thymic precursors migrate from the bone marrow to the thymus, the T lineage commitment is initiated. Determined by the levels of surface receptors CD4 and CD8, the development of T cells is divided into a ...
The transport of ions is an essential biological process that helps to maintain healthy biological processes such as ion homeostasis, pH gradients, and membrane polarization. In a natural system, this vital function is ...
Earlier work from our lab has shown that type 2 diabetes mellitus (T2DM) progression is not majorly dependent on insulin-glucose deregulation. A network model by Dr. Shubhankar Kulkarni revealed that in absence of multi-organ ...
The impacts of ocean warming are increasingly noticeable in the Arctic, such as the retreat of ice sheets and the accelerated melting of glaciers. The marine sediments in the Fram Strait gateway, connecting the Arctic and ...
Plants often fend off insect herbivores using induced chemical defenses. Several small RNAs, including microRNAs (miRNAs), are also induced in plants after herbivory. Since the herbivore ingests the small RNAs induced in ...
We have tried to optimize the growth parameters of the CVD growth of Bi2O2Se on various substrates, focusing on f-mica. Also, exploring the various techniques of Photolithography to signify the vital role it plays in 2D ...
Thioglycosylation, a versatile synthetic method for the formation of glycosidic bonds using thioglycosides as donors, has emerged as a powerful tool in carbohydrate chemistry. This abstract provides an overview of ...
The first part of the thesis is mainly a literature study of the book, ”Exact Exponential Algorithms” by Fomin and Krastch. We explain different techniques to solve computational problems through exact algorithms. The ...
Long non-coding RNAs (lncRNAs) are RNA molecules longer than 200 nucleotides that do not code for proteins, but have been shown to perform regulatory roles in various cellular processes and in disease conditions. They have ...
High Grade Serous Ovarian Cancer (HGSOC) is one of the most lethal gynaecological malignancies with a 5-year survival rate of less than 42%. Current treatment regimens against the disease include debulking surgeries, Neo ...
Escape behaviours are severely time-constrained due to fast predatory strikes. They thus provide a useful model to understand how different behaviour strategies are computed over a limited number of synapses. Broadly, one ...
The impacts of climate change are felt by most critical systems, such as infrastructure, ecological systems, and power plants. However, contemporary Earth System Models (ESM) are run at spatial resolutions too coarse for ...
This section contains abstracts of projects done for completion of my MS thesis. Project 1: Molecular interaction of SARS-CoV-2 mutants binding to the human ACE2 receptor using AFM
The main project of this thesis is ...
Phagocytosis is an evolutionarily conserved pathway to degrade foreign pathogens and apoptotic cells. This process is highly driven by the lipid metabolism where cholesterol plays an important role. Although the role of ...
A recent study in Caulobacter crescentus, a dimorphic bacterial model to study cell cycle in prokaryotes, revealed the existence of a dynamic cytoplasmic redox and its importance in cell cycle progression. It was demonstrated ...