Theses submitted to IISER Pune in partial fulfilment of the requirements of the BS-MS dual degree and Ph.D programmes. Also, project reports submitted by the students.
Mixed Rossby-gravity (MRG) waves are tropical synoptic-scale disturbances which exhibit mixed properties of low frequency Rossby waves and high frequency gravity waves. A comprehensive understanding on the major factors ...
Heparan sulfate (HS) is a negatively charged polysaccharide, widely present on the surface of all mammalian cells and in the extracellular matrix. Depending on the sulfation patterns and uronic acid compositions, the HS ...
Information gathered by sensory organs is processed in the specialized pre-cortical and cortical areas, ultimately leading to animals’ behavioural responses. For rodents, olfaction (sense of smell) has been proven to be a ...
Pāṇini's Aṣṭādhyāyī is a rule book that employs many techniques to derive the Sanskrit language. One such technique is the principle of suspension (asiddhatva). This principle is predominantly used in the last three quarters ...
Macrocyclic compounds are large-sized cyclic structures constituted by more than 12 atoms and are found as important scaffolds in medicine, materials, sensors, and catalysis applications. Macrocycles are also important ...
Automated quantification of microscopy datasets plays an important role in understanding biological phenomena. This requires robust computational methods for accurate object detection, tracking, and segmentation. In this ...
The group 14 elements, known as N-heterocyclic tetrylenes (NHTs), typically have six electrons in their valence shell. They are currently one of the most rigorously investigated groups of ancillary ligands in modern ...
Cancer cells are unique in overcoming the requirement for cell-matrix adhesion (anchorage dependence) to grow, proliferate and metastasize. Among the cellular pathways regulated by adhesion include its ability to control ...
Nature is the biggest source of bioactive macrocyclic compounds, which have an indispensable impact on human lives. Currently, many approved drugs feature a macrocycle moiety as their bioactive core. Furthermore, macrocycles ...
Invasive species are a leading cause of biodiversity loss, and identifying and prioritizing invasive species for management are major goals set by the Convention on Biodiversity (CBD, 2010). While steps towards this have ...
Carbohydrates, which are ubiquitously distributed throughout the three domains of life, play significant roles in a variety of vital biological processes. Access to unique and homogeneous carbohydrate materials is important ...
Chemical and biological processes are stochastic and intrinsically heterogeneous at both microscopic and mesoscopic levels. The present thesis investigates the microscopic mechanisms of such processes using discrete-state ...
Self-assembling cyclic peptides are important building blocks for constructing synthetic nanotubes. They can be primarily classified into D, L-cyclic peptides, cyclic β-peptides, cyclic α, γ-peptides, and cyclic peptides ...
The first-passage time of a stochastic time-series, defined to be the time taken by it to cross a predefined threshold for the first time, has a wide range of applications across disciplines. However, if the time-series ...
Heparan sulfate proteoglycans (HSPGs) are essential components of the extracellular matrix and cell surfaces, playing pivotal roles in various biological processes. Composed of a core protein with covalently attached heparan ...
In the evolving landscape of modern precision cosmology, the continuous progress of ongoing and upcoming surveys has provided us with an unprecedented level of statistical power or drawing robust inference. The study of ...
Let K = Q(
Ô≠d) where d(> 0) is a square-free integer. Let OK be the ring of integers
of K.
Consider the hyperbolic 3-space H3 ( Upper half space),
H3 := {(z, t) œ C ◊ R | t > 0}.
We define the extended 3- dimensional ...
As the early thymic precursors migrate from the bone marrow to the thymus, the T lineage commitment is initiated. Determined by the levels of surface receptors CD4 and CD8, the development of T cells is divided into a ...
The transport of ions is an essential biological process that helps to maintain healthy biological processes such as ion homeostasis, pH gradients, and membrane polarization. In a natural system, this vital function is ...
Earlier work from our lab has shown that type 2 diabetes mellitus (T2DM) progression is not majorly dependent on insulin-glucose deregulation. A network model by Dr. Shubhankar Kulkarni revealed that in absence of multi-organ ...