Theses submitted to IISER Pune in partial fulfilment of the requirements of the BS-MS dual degree and Ph.D programmes. Also, project reports submitted by the students.
The Membrane-associated Periodic Skeleton (MPS) is a critical cytoskeletal structure observed in diverse neuronal subtypes across multiple species. Since its identification in 2013, it has been demonstrated to be essential ...
Diazo compounds are highly versatile as well as valuable reagents whose reactivity can be fine-tuned through metal catalysis, photochemical activation, and radical pathways to enable divergent and selective synthetic ...
Nature has always been the underlying inspiration for various solar energy conversion technologies and among them, solar-to-chemical energy conversion in photosynthesis is considered to be the most elegant way to make ...
In recent years, algebraic quantum field theory (AQFT) and modular theory have provided significant insights into gravitational degrees of freedom. Notably, the works [1–3] demonstrate that the inclusion of gravitational ...
One of the goals of early universe cosmology is to understand the physics of inflation. Since we cannot visually access this epoch, we rely on indirect observations, e.g., measuring temperature correlations on the CMB. By ...
The revival of radical chemistry in organic synthesis has fuelled a renaissance in visible-light photoredox catalysis. This mild and versatile approach has rapidly gained traction across diverse fields, from biomedical ...
Understanding the behavior of time-evolving systems is central to contemporary data science, with wide-ranging applications in domains such as finance, biology and environmental studies. These systems are often high-dimensional, ...
Light carries energy, linear momentum, and angular momentum, which can be directly transferred to microscopic and nanoscopic objects. This transfer allows precise control and manipulation of their motion by suppressing ...
Fluctuations play a crucial role in the operation of small-scale devices, where thermal and quantum effects significantly influence the efficiency, power output, and stability of machines. This thesis investigates performance ...
Quantum-level energy storage and usage is gaining significant interest among scientific communities with a newly introduced concept in quantum thermodynamics, namely ergotropy. Ergotropy quantifies the maximum amount of ...
Proteins, through their activity and interactions, are the predominant class of molecules enabling the functioning of the living cell. They are linear polymers of amino acids that fold based on covalent and non-covalent ...
The standard model of particle physics (SM) describes fundamental particles and their interactions. The predictions of the SM have been extensively tested in the experiments. However, it does not explain key phenomena such ...
The cell wall of Mycobacterium tuberculosis is a complex structure composed of lipids, glycolipids, polysaccharides, and proteins. Key components include peptidoglycans (PG), lipoarabinomannan (LAM), and mycolyl arabinogalactan ...
FtsZ and FtsA are the two primary components of the Z-ring involved in bacterial cell division. Despite extensive research, their roles in driving cell constriction are not well defined. In this context, FtsZ and FtsA from ...
Understanding the mechanism of evolution of continents- comprising Archean Cratons flanked by younger mobile belts- through time is challenging. Cratons have a cold, thick, buoyant lithosphere, which remained stable for ...
Chirality is an important fundamental property of molecular systems that is crucial in various fields, including chemistry, pharmacology, biology, and materials science. Research activities involving chiral recognition and ...
The bacterial ATP-dependent restriction enzymes use energy derived from the hydrolysis of ATP to cleave double-stranded DNA (dsDNA), usually between two specific target sequences. Nucleolytic cleavage of the DNA by the ...
RALA (RAS Like Proto-Oncogene A) is a RAS family small GTPase that regulates vital cellular processes like cell spreading, migration and proliferation. Downstream of RAS, activation of RALA is critical for cancer cell ...
The evolutionarily conserved vacuolar protein sorting (VPS) pathway prescribes a mechanism by which newly synthesized proteins are delivered from the Golgi apparatus to the lysosomes/vacuole and back via endosomes. Originally ...
Proteins exist as ensembles of multiple states within a free energy landscape, where partially unfolded forms (PUFs) are present alongside the stable, folded native state (N). These PUFs arise through protein dynamics and ...