Theses submitted to IISER Pune in partial fulfilment of the requirements of the BS-MS dual degree and Ph.D programmes. Also, project reports submitted by the students.
Protein folding is a heterogeneous process in which multiple conformational sub-populations coexist within unfolded, intermediate, and native ensembles. However, the molecular determinants that give rise to this heterogeneity ...
Animals exhibit instinctive and learned stimulus-guided behaviours to adapt to dynamic environments. These innate and learned behaviours engage different cortical brain regions; however, how the sensory processing area ...
Modern deep learning weather prediction models excel in prediction speed as well as accuracy. Among these Spherical Fourier Neural Operators have emerged as a promising architecture that implicitly model underlying atmospheric ...
Emotional responses such as fear and anxiety are regulated by intricate neural circuits that are modulated by various neuromodulators, including dopamine. Dopamine signaling in brain regions such as the basolateral amygdala ...
The Rampur-Bushahr region in Himachal Pradesh hosts the Rampur Tectonic Window, where Lesser Himalayan metasediments are exposed within the Greater Himalayan Crystalline sequence. Although such windows are attributed to ...
Protein interactions are fundamental to life, and the capability to engineer such interactions has immense potential for therapeutics and synthetic biology. Established methods for screening protein binders, such as yeast ...
The actin fold is highly conserved in eukaryotes, whereas it is diverged in homologs with less than 15 per cent sequence identity and specialised for different functions in prokaryotes. Despite sharing the common actin ...
Honeybees (Apis mellifera) are known to possess magnetic sensitivity, yet the neural and biochemical mechanisms underlying magnetoreception remain poorly understood. The radical pair mechanism (RPM), a quantum-mechanical ...
Layered 2D semiconductors and magnets demonstrate novel excitonic physics. Their magnetic properties can be effectively studied at low fields using differential spectroscopy techniques such as Faraday effect and magneto-optic ...
Complex (dusty) plasmas serve as exceptional macroscopic analogues for studying the nonlinear dynamics of strongly coupled fluids and warm dense matter. While computational modelling provides deep insights into these ...
Understanding how environmental gradients shape morphological variation is a central question that links to ecology, evolution, and species responses to climate change. We investigated the relationship between climate and ...
Predicting the tertiary structure of the peptides with non-canonical amino acids (NCAAs) remains a big hurdle in computational biology, despite it being a rapidly growing class of therapeutics. Existing methods for peptide ...
This study examines the patterns of Multidimensional Poverty reduction in Indian districts between NFHS 4 and NFHS 5 and explores the factors associated with these changes District level figures of Multidimensional Poverty ...
Alcoholic Steatohepatitis (ASH) is gradually advancing alcoholic liver disease (ALD) with hepatosteatosis, inflammation, and fibrosis. However, the molecular mechanism of ASH is incompletely understood. The orphan nuclear ...
Plants and insects interact with each other in the environment, and among these interactions, plant insect herbivore interactions are of considerable ecological and agricultural consequences. Plants have a rich repertoire ...
The global energy crisis and the massive waste of thermal energy across industrial, transportation, and consumer systems have renewed urgency around the development of efficient thermoelectric materials — solid-state devices ...
Live bivalve communities are sensitive indicators of shallow marine ecosystem health, as they are influenced by pollution and seasonal changes. Yet studies simultaneously evaluating both stressors on shallow marine communities ...
Climate change has been affecting the most essential resources, including food, water, and energy, creating an urgency for adaptation. Additionally, power dynamics determine how these resources are distributed across the ...
The Indian summer Monsoon (ISM) is evolving over time, with a westward shift in precipitation, creating a dipole-like structure with an increase (decrease) in precipitation over the Northwest (Northeast) regions, which has ...
Grasping the local structural features responsible for protein stability is essential for engineering robust biomolecules for industrial and therapeutic use. The presence of “cliques” groups of amino acids in close proximity ...