Theses submitted to IISER Pune in partial fulfilment of the requirements of the BS-MS dual degree and Ph.D programmes. Also, project reports submitted by the students.
The transport of ions is an essential biological process that helps to maintain healthy biological processes such as ion homeostasis, pH gradients, and membrane polarization. In a natural system, this vital function is ...
Earlier work from our lab has shown that type 2 diabetes mellitus (T2DM) progression is not majorly dependent on insulin-glucose deregulation. A network model by Dr. Shubhankar Kulkarni revealed that in absence of multi-organ ...
The impacts of ocean warming are increasingly noticeable in the Arctic, such as the retreat of ice sheets and the accelerated melting of glaciers. The marine sediments in the Fram Strait gateway, connecting the Arctic and ...
Plants often fend off insect herbivores using induced chemical defenses. Several small RNAs, including microRNAs (miRNAs), are also induced in plants after herbivory. Since the herbivore ingests the small RNAs induced in ...
We have tried to optimize the growth parameters of the CVD growth of Bi2O2Se on various substrates, focusing on f-mica. Also, exploring the various techniques of Photolithography to signify the vital role it plays in 2D ...
Thioglycosylation, a versatile synthetic method for the formation of glycosidic bonds using thioglycosides as donors, has emerged as a powerful tool in carbohydrate chemistry. This abstract provides an overview of ...
The first part of the thesis is mainly a literature study of the book, ”Exact Exponential Algorithms” by Fomin and Krastch. We explain different techniques to solve computational problems through exact algorithms. The ...
Long non-coding RNAs (lncRNAs) are RNA molecules longer than 200 nucleotides that do not code for proteins, but have been shown to perform regulatory roles in various cellular processes and in disease conditions. They have ...
High Grade Serous Ovarian Cancer (HGSOC) is one of the most lethal gynaecological malignancies with a 5-year survival rate of less than 42%. Current treatment regimens against the disease include debulking surgeries, Neo ...
Escape behaviours are severely time-constrained due to fast predatory strikes. They thus provide a useful model to understand how different behaviour strategies are computed over a limited number of synapses. Broadly, one ...
The impacts of climate change are felt by most critical systems, such as infrastructure, ecological systems, and power plants. However, contemporary Earth System Models (ESM) are run at spatial resolutions too coarse for ...
This section contains abstracts of projects done for completion of my MS thesis. Project 1: Molecular interaction of SARS-CoV-2 mutants binding to the human ACE2 receptor using AFM
The main project of this thesis is ...
Phagocytosis is an evolutionarily conserved pathway to degrade foreign pathogens and apoptotic cells. This process is highly driven by the lipid metabolism where cholesterol plays an important role. Although the role of ...
A recent study in Caulobacter crescentus, a dimorphic bacterial model to study cell cycle in prokaryotes, revealed the existence of a dynamic cytoplasmic redox and its importance in cell cycle progression. It was demonstrated ...
The pitfall of the existing energy grid system such as global warming, depletion of fossil fuel resources, and paramount pollution mandate the focus on renewable, and sustainable energy resources. The hydrogen economy is ...
p-adic numbers play an important role in modern number theory. They encode important information about congruences between integers. From rational number, one construct the smallest complete field that contains rational ...
The study aims to understand the cognitive abilities that would constitute an ideal aspirant for Higher Education in STEM. Building up on the idea that aptitude can be understood in terms of abilities, we analyse the ...
In biological systems, different types of nitrite reductase (NiRs) and nitric oxide synthase (NOS) isozymes are present to generate NO for physiological activities. To mimic this function, we choose the acid-induced path ...
In this thesis, we study the entanglement phase transition from volume-law to area-law entanglement in a hard-core boson chain model under continuous measurement of local occupation number. We are specifically interested ...
Proteins are essential for numerous biological activities, with their functions often modulated by the binding of small molecules. Understanding protein-ligand interactions is thus vital for gaining insights into protein ...