TopBP1 is an important mediator protein involved in the cell cycle checkpoint signaling pathway that is activated when there are single strand lesions on DNA. TopBP1 has structural and functional similarity to BRCA1 (a ...
DNA topoisomerase IIβ -binding protein 1 (TopBP1) is a mediator protein that regulates cell cycle checkpoint signaling pathway. A plethora of studies suggest that TopBP1 protein levels are high and positively associated ...