• Age-dependent neuroinflammation in a Drosophila model of Amyotrophic Lateral Sclerosis 8 

  KULKARNI, NAMRATA (2026-04)

  Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disorder marked by progressive loss of motor function. It is a multigenic disease with complex pathophysiology, diverse clinical manifestations and multifactorial ...
• Fibrillarin - a Central Regulator of Epithelial Integrity and Tumor Progression 

  SAHA, SANTAM (2026-04)

  Epithelial integrity is maintained through coordinated regulation of cell–cell adhesion, apico basal polarity, and transcriptional programs that preserve epithelial identity. Disruption of these processes underlies ...
• Regulation of Epithelial-Mesenchymal Plasticity through Lamin A/C and EZH2 phosphorylation 

  AK, BALAJI (2026-04)

  Epithelial-to-Mesenchymal Transition (EMT) and its reverse, Mesenchymal-to-Epithelial Transition (MET), underlie essential physiological processes, such as development and wound healing, while also driving pathological ...
• Chemical Synthesis and Functional Characterization of Fluorinated Heparan Sulfate Fragments and Fondaparinux-Based Glycomimetics. 

  MAHIDA, VIRENDRASINH (2026-04)

  The glycocalyx, a dense layer of glycans on the cell surface, plays a fundamental role in mediating cellular communication, adhesion, and signal transduction. Among its key constituents, heparan sulfate (HS) is a highly ...
• Design of Peptide Antibiotics and Aβ-42 Aggregation Inhibitors with Extended Longevity 

  TORASKAR, SANDIP (2026-04)

  Peptides offer several advantages in drug discovery due to their ability to mimic natural biological molecules, enabling high target specificity and potency. Their biological activity is influenced by sequence, structure, ...
• Biochemical and structural characterization of Myxococcus xanthus Frz chemosensory receptor complex 

  DAS, APURBA (2026-04)

  In bacterial chemotaxis, methyl-accepting chemotaxis proteins (MCPs) detect environmental cues and initiate a phosphorelay signal. In Myxococcus xanthus, the Frz pathway regulates motility in response to these cues. MCPs ...
• Structural and topological defects governing plastic deformation in colloidal glasses under shear 

  SAHU, RATIMANASEE (2026-04)

  Defects play a fundamental role in determining the mechanical behavior of materials. In crystalline solids, their nature and dynamics are well understood, as dislocations and vacancies mediate plastic deformation. However, ...
• Crowding and evolutionary divergence in microtubule assembly and combinatorial effects in kinesin-1 transport. 

  BASU, JASHASWI (2026-04)

  Microtubule (MT) polymerization and motor driven transport drive cellular processes like intracellular transport and cell division. In this thesis, we study how physical and chemical factors collectively affect microtubule ...
• BIOCHEMICAL CHARACTERISATION OF ABHD14A: AN ORPHAN PROTEIN 

  GUPTA, SONALI (2026-03)

  The advent of genome sequencing technologies has revealed the presence of a myriad of proteins in the mammalian system, many of which are poorly characterised. The presence of these orphan proteins imply that our understanding ...
• First-Principles Investigation of Entropy-stabilized and Double Half-Heusler Alloys for Thermoelectric Applications 

  RANJAN, RAJEEV (2026-03)

  This thesis presents two projects centered on the computational design and analysis of thermoelectric materials derived from half-Heusler and double half-Heusler compounds. The research is motivated by the growing need to ...
• DESIGN AND SYNTHESIS OF BIO-SIGNALING LIPIDS AND THEIR BIOACTIVE PROBES 

  THAKRAL, POOJA (2026-03)

  Lipids molecules often share highly similar structural frameworks among species, however minor variation in their chemical composition influence their interactions with proteins interactors. Many of these interactions are ...
• Transport under coordinate-dependent diffusion: An Itô Perspective 

  SHARMA, MAYANK (2026-03)

  Biological systems at micrometer scales and below often operate in crowded, highly viscous environments characterized by persistent stochastic thermal fluctuations. Diffusion is incessant and plays an important role in ...
• Intraseasonal convective initiations – precursors and predictability 

  SIMON, DANIEL (2026-03)

  The equatorial Indian Ocean is widely recognized as a key region for Madden–Julian Oscillation (MJO) convective initiation, but it does not behave as a single, uniform initiation basin. Instead, strong zonal and seasonal ...
• Understanding the variations in strength and extent of regional Hadley circulations 

  BARUAH, PRATIKSHA PRIYAM (2026-02)

  The zonal-mean representation of the Hadley circulation provides a simple and effective framework for describing the global tropical circulation. However, such zonal averaging may obscure important regional meridional ...
• Design and Synthesis of Ultramicroporous Zinc-azolate-based MOFs for Selective CO2 Capture 

  SINGH, PIYUSH (2026-02)

  Global warming remains a significant challenge, primarily caused by greenhouse gases such as CO₂, CH₄, and N₂O, which trap heat in the atmosphere. Since the industrial revolution, CO₂ levels have risen from approximately ...
• Elucidating the Role of Single-Chain Amphiphiles in Dynamical Soft-Matter Systems: From Life’s Origins to Biological Applications 

  DAS, SOURADEEP (2026-02)

  Single-chain amphiphiles (SCAs) based vesicle systems are endowed with interesting properties like high dynamicity of membranes, making these systems more amenable to molecular/chemical evolution and exciting as ...
• Phase Transition, Doping (Mn2+ and Mo3+) and Luminescence of Cs2NaBiCl6 and CH3NH3PbBr3 Perovskites: Bulk and Nanocrystals 

  BANERJEE, SRIJITA (2026-02)

  Halide perovskites often change their crystal structure based on external condition like temperature and pressure. This structural phase transition may lead to changes in their inherent semiconducting properties like ...
• Conducting Covalent Organic Frameworks with Potential for Energy Storage & Metal-Cluster Embedded COFs for CO2 Reduction Reaction 

  JAIN, CHITVAN (2026-02)

  Covalent Organic Frameworks (COFs) are an emerging class of crystalline porous polymers constructed via reticular chemistry, offering a modular platform with tunable porosity, high surface area, and excellent thermal and ...
• Electrodeposition of Metal-Organic Framework Thin Films: Design, Fabrication, and Applications 

  BHOI, UMASHIS (2026-02)

  Metal-organic frameworks (MOFs) are a distinctive class of hybrid organic-inorganic materials composed of periodically arranged metal nodes and organic linkers. These materials have attracted considerable attention across ...
• Landscape scale variability in vegetation and soil organic carbon dynamics in the Western Ghats 

  DEVI, SALAM MAHESHWORI (2026-02)

  Soil organic carbon (SOC) is the largest terrestrial carbon reservoir (1550 GT), holding more carbon than that by biomass and atmosphere. Despite being a key component of the global carbon cycle, large uncertainty remains ...

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