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  • Role of SATB1 in T cell development and differentation 
    GOTTIMUKKALA, KAMALVISHNU PRASAD (Dept. of Biology, 2013-08)
    T lymphocyte development and differentiation is a multi-step process that begins in the thymus and completed in the periphery. Sequential development of thymocytes is dependent on T cell receptor (TCR) signaling and an ...
  • Comparative study of SATB family proteins 
    SINGH, SUNITA (Dept. of Biology, 2013-08)
    SATB1 and SATB2 are members of special AT-rich binding protein family, a class of chromatin organizers and gene regulators. SATB1 has been shown to play seminal roles in development and differentiation of T cells whereas ...
  • Role and Regulation of SATB1 in colorectal tumorigenesis and progression 
    MIR, RAFEEQ (Dept. of Biology, 2015-11)
    Tumor development and metastasis involves programmed and progressive changes in expression of large number of genes. The precise molecular mechanisms and signaling pathways regulating the expression of these genes are ...
  • Regulation of Wnt/Wg signaling pathway by chromatin organizer SATB1 
    PRAVEENA, R. L. (Dept. of Biology, 2016-05)
    Abstract: Special AT-rich binding protein 1 (SATB1) is a global chromatin organizer that links higher-order chromatin architecture to gene regulation. In addition to its key role in gene regulation, it is also known to ...
  • Regulation of chromatin organizer SATB1 via TCR induced alternative promoter switch during T- cell development 
    PATTA, INDUMATHI (Dept. of Biology, 2019-07)
    SATB1 is a T-lineage-enriched chromatin organizer and global gene regulator. SATB1 regulates multitude of genes important for T-cell survival, positive and negative selection. SATB1 binds to its target loci and recruits ...
  • Understanding molecular mechanisms of T-helper 17 differentiation 
    SHETTY, ANKITHA (Dept. of Biology, 2020-12)
    Pro-inflammatory Th17 cells are critical for mucosal immune responses and also have implications in development of autoimmune disorders. So far, Th17 regulatory networks have been investigated using mouse models, but the ...

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