Specific interactions between DNA and proteins mediate many crucial processes in biological systems. The basis for this specificity is only known for certain protein families such as zinc fingers and transcription ...

Extensive efforts have been made over the years to design protein structure mimetics using a variety of unnatural amino acid building blocks. The advancement in the field of peptide foldamers not only facilitated understanding ...

Vitamin B12 belongs to the cobamides family of cofactors required by several organisms including bacteria, archaea, protists, algae, and animals. Cobamides act as cofactors for methyl transfer and radical-based reaction ...

Thesis Abstract: Title: Development of biomimetic photo-responsive artificial carriers for the transmembrane chloride transport The transport of ions across the cell membrane through naturally occurring ion carriers and ...

Choline is an essential nutrient for mammalian cells that acts as a substrate for Kennedy pathway, wherein, upon cellular internalization, it is sequentially converted into phosphocholine and cytidine 5'-diphosphocholine ...

Over the years photoredox catalysis has gained a great importance and the same has been explored for many transformations. Different organosulfur compounds have been employed for different transformations using photoredox ...

Secondary structures of peptides/proteins are governed by the hydrogen bonding interactions in the backbone as well as sequence of the amino acid residues present there. The most common secondary structures observed in ...

In Drosophila, NF-κB signaling plays key roles in both animal development and in host defence. The activation and kinetics of the two main arms of NF-κB, the Toll and IMD pathways are regulated by post-translational ...

Lamin B Receptor (LBR) is an integral protein of the inner nuclear membrane required for nuclear envelope reassembly post-mitosis. LBR and lamins are associated with heterochromatin at the nuclear envelope thereby modulating ...

The thesis entitled “Structural control of Peptide Nucleic Acid (PNA) rotamers and their fluorescence properties: aza-PNA, gemdimethyl G-PNA and Cα(S)-bm PNA monomers and oligomers” describes studies done on the synthesis, ...