Design, synthesis and evaluation of small molecule reactive oxygen species generators as selective Mycobacterium tuberculosis inhibitors

dc.contributor.author	DHARMARAJA, ALLIMUTHU T.	en_US
dc.contributor.author	Alvala, Mallika	en_US
dc.contributor.author	Sriram, Dharmarajan	en_US
dc.contributor.author	Yogeeswari, Perumal	en_US
dc.contributor.author	CHAKRAPANI, HARINATH	en_US
dc.date.accessioned	2020-10-19T04:12:47Z
dc.date.available	2020-10-19T04:12:47Z
dc.date.issued	2012-10	en_US
dc.identifier.citation	Chemical Communications, 48(83), 10325-10327.	en_US
dc.identifier.issn	1359-7345	en_US
dc.identifier.issn	1364-548X	en_US
dc.identifier.uri	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/5159
dc.identifier.uri	https://doi.org/10.1039/C2CC35343A	en_US
dc.description.abstract	Here, we report 5-hydroxy-1,2,3,4,4a,9a-hexahydro-1,4-ethano-9,10-anthraquinone (13), a small molecule generating reactive oxygen species (ROS) in pH 7.4 buffer under ambient aerobic conditions that has selective and potent Mycobacterium tuberculosis growth inhibitory activity.	en_US
dc.language.iso	en	en_US
dc.publisher	Royal Society of Chemistry	en_US
dc.subject	Chemistry	en_US
dc.subject	2012	en_US
dc.title	Design, synthesis and evaluation of small molecule reactive oxygen species generators as selective Mycobacterium tuberculosis inhibitors	en_US
dc.type	Article	en_US
dc.contributor.department	Dept. of Chemistry	en_US
dc.identifier.sourcetitle	Chemical Communications	en_US
dc.publication.originofpublisher	Foreign	en_US