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Capturing a novel metastable polymorph of the anticancer drug gefitinib

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dc.contributor.author Thorat, Shridhar H. en_US
dc.contributor.author Patwadkar, Manjusha V. en_US
dc.contributor.author Gonnade, Rajesh G. en_US
dc.contributor.author VAIDHYANATHAN, RAMANATHAN en_US
dc.date.accessioned 2020-10-20T07:06:50Z
dc.date.available 2020-10-20T07:06:50Z
dc.date.issued 2014-10 en_US
dc.identifier.citation Crystengcomm, 16(37), 8638-8641. en_US
dc.identifier.issn 1466-8033 en_US
dc.identifier.uri http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/5210
dc.identifier.uri https://doi.org/10.1039/C4CE01446D en_US
dc.description.abstract Gefitinib, a life-extending anticancer drug, exhibits solvent-mediated conformational polymorphism to yield stable (form I) and novel metastable (form II) polymorphs. Crystal structure analysis revealed 3D isostructurality in the molecular organization of the polymorphs, and the metastable polymorph undergoes a crystal-to-crystal thermal phase transition to the stable polymorph. en_US
dc.language.iso en en_US
dc.publisher Royal Society of Chemistry en_US
dc.subject Chemistry en_US
dc.subject 2014 en_US
dc.title Capturing a novel metastable polymorph of the anticancer drug gefitinib en_US
dc.type Article en_US
dc.contributor.department Dept. of Chemistry en_US
dc.identifier.sourcetitle Crystengcomm en_US
dc.publication.originofpublisher Foreign en_US


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