Effect of hematocrit on blood dynamics on a compact disc platform

Abstract

We investigate blood flow dynamics on a rotationally actuated lab-on-a-compact disk (LOCD) platform, as a function of the hematocrit level of the blood sample. In particular, we emphasize the resultant implications on the critical fluidic parameters, such as on burst frequency and volumetric flow rate. Our results can be utilized as a characteristic guideline to predict the hematological parameters of a given small amount of blood sample from the observed flow characteristics, and can give rise to a new paradigm of medical diagnostics driven by interactions between blood rheology and rotational forces on an inexpensive platform, with minimal sample consumption.