Author

Sort by: Order: Results:

  • Combining Information from Crosslinks and Monolinks in the Modeling of Protein Structures 
    Sinnott, Matthew; Malhotra, Sony; MADHUSUDHAN, M. S.; Thalassinos, Konstantinos; Topf, Maya (Elsevier B.V., 2020-09)
    Monolinks are produced in a chemical crosslinking mass spectrometry experiment and are more abundant than crosslinks. They convey residue exposure information, but so far have not been used in the modeling of protein ...
  • Peptide bond planarity constrains hydrogen bond geometry and influences secondary structure conformations 
    Tan, Kuan Pern; SINGH, KHUSHBOO; HAZRA, ANIRBAN; MADHUSUDHAN, M. S. (Elsevier B.V., 2021)
    An extensive database study of hydrogen bonds in different protein environments showed systematic variations in donor-acceptor-acceptor antecedent angle (Ĥ) and donor-acceptor distance. Protein environments were characterized ...
  • Observation of an Unusually Large IR Red-Shift in an Unconventional S–H···S Hydrogen-Bond 
    MISHRA, KAMAL K.; BORISH, KSHETRIMAYUM; SINGH, GULZAR; PANWARIA, PRAKASH; METYA, SURAJIT; MADHUSUDHAN, M. S.; DAS, ALOKE (American Chemical Society, 2021-02)
    The S–H···S non-covalent interaction is generally known as an extremely unconventional weak hydrogen-bond in the literature. The present gas-phase spectroscopic investigation shows that the S–H···S hydrogen-bond can be as ...
  • Methods for Molecular Modelling of Protein Complexes 
    KANITKAR, TEJASHREE RAJARAM; SEN, NEELADRI; NAIR, SANJANA; SONI, NEELESH; AMRITKAR, KAUSTUBH; YAMTIRTHA, YOGENDRA; MADHUSUDHAN, M. S. (Springer Nature, 2021-05)
    Biological processes are often mediated by complexes formed between proteins and various biomolecules. The 3D structures of such protein–biomolecule complexes provide insights into the molecular mechanism of their action. ...
  • The miRISC component AGO2 has multiple binding sites for Nup358 SUMO-interacting motif 
    Deshmukh, Prachi; Markande, Shubha; Fandade, Vikas; RAMTIRTHA, YOGENDRA; MADHUSUDHAN, M. S.; Joseph, Jomon (Elsevier B.V., 2021-06)
    Micro-RNA mediated suppression of mRNA translation represents a major regulatory mode of post-transcriptional gene expression. Recently, the nucleoporin Nup358 was shown to interact with AGO protein, a key component of ...
  • On and off controls within dynein–dynactin on native cargoes 
    Sanghavi, Paulomi; Kumar, Pankaj; ROY, ANKIT; MADHUSUDHAN, M. S.; Mallik, Roop (National Academy of Sciences, 2021-06)
    The dynein–dynactin nanomachine transports cargoes along microtubules in cells. Why dynactin interacts separately with the dynein motor and also with microtubules is hotly debated. Here we disrupted these interactions in ...
  • Packpred: Predicting the Functional Effect of Missense Mutations 
    Tan, Kuan Pern; KANITKAR, TEJASHREE RAJARAM; Kwoh, Chee Keong; MADHUSUDHAN, M. S. (Frontiers Media S.A, 2021-08)
    Predicting the functional consequences of single point mutations has relevance to protein function annotation and to clinical analysis/diagnosis. We developed and tested Packpred that makes use of a multi-body clique ...
  • PDBe-KB: collaboratively defining the biological context of structural data 
    Varadi, Mihaly; MADHUSUDHAN, M. S.; SINGH, GULZAR et al. (Oxford University Press, 2022-01)
    The Protein Data Bank in Europe – Knowledge Base (PDBe-KB, https://pdbe-kb.org) is an open collaboration between world-leading specialist data resources contributing functional and biophysical annotations derived from or ...
  • A structural database of chain–chain and domain–domain interfaces of proteins 
    SEN, NEELADRI; MADHUSUDHAN, M. S. (Wiley, 2022-09)
    In this study, we mined the PDB and created a structural library of 178,465 interfaces that mediate protein–protein/domain–domain interactions. Interfaces involving the same CATH fold(s) were clustered together. Our analysis ...
  • Identification of sequence determinants for the ABHD14 enzymes 
    VAIDYA, KAVERI; RODRIGUES, GOLDING; GUPTA, SONALI; Devarajan, Archit; YEOLEKAR, MIHIKA; MADHUSUDHAN, M. S.; KAMAT, SIDDHESH S. (Wiley, 2023-11)
    Over the course of evolution, enzymes have developed remarkable functional diversity in catalyzing important chemical reactions across various organisms, and understanding how new enzyme functions might have evolved remains ...

Search Repository


Advanced Search

Browse

My Account