Wenger, Eliott S.; SIL, DEBANGSU; SILAKOV, ALEXEY et al.
(American Chemical Society, 2024-08)
Hyoscyamine 6β-hydroxylase (H6H) is an iron(II)- and 2-oxoglutarate-dependent (Fe/2OG) oxygenase that produces the prolifically administered antinausea drug, scopolamine. After its namesake hydroxylation reaction, H6H then ...