Nandurdikar, Rahul S.; Maciag, Anna E.; Hong, Sam Y.; CHAKRAPANI, HARINATH; Citro, Michael L.; Keefer, Larry K.; Saavedra, Joseph E.
(American Chemical Society, 2009-12)
GlcNAc-PROLI/NO prodrugs that are activated by N-acetylglucosaminidase to release nitric oxide (NO) are described. A classical acid-amine coupling is used to bifunctionalize these PROLI/NO prodrugs, which on activation ...