Proper formation and specification of Primordial Germ Cells (PGCs) is of special significance as they gradually transform into Germline Stem Cells (GSCs) that are ultimately responsible for generating the gametes. Intriguingly, ...

Light chain (AL) amyloidosis is the most common systemic amyloid disease characterized by abnormal accumulation of amyloid fibrils derived from immunoglobulin light chains (LCs). Both full-length (FL) LCs and their isolated ...

Both immunoglobulin light-chain (LC) amyloidosis (AL) and multiple myeloma (MM) share the overproduction of a clonal LC. However, while LCs in MM remain soluble in circulation, AL LCs misfold into toxic-soluble species and ...

Two-dimensional organic materials are mainly constructed by using orthogonal anisotropic connectivity of covalent bonding and π–π stacking. The noncovalent connectivity between building blocks is presumed to be too delicate ...

Optical tweezers have revolutionized particle manipulation at the micro- and nanoscale, playing a critical role in fields such as plasmonics, biophysics, and nanotechnology. While traditional optical trapping methods ...

The recovery of radioactive iodine from nuclear waste and contaminated water sources is a critical environmental concern, which poses significant technical challenges. Herein, the study has demonstrated that tuning the ...

Herein, we introduced a series of carbonohydrazonoyl dicyanide-linked indole carboxamide 1a–1c transporters. Detailed mechanistic insight into the transport manifested that superior transporter 1a facilitates the movement ...

Molecular ferroelectrics are of enormous interest due to their ease of synthesis and simplicity in device fabrication. Here, the non-volatile memory effect in a polycrystalline thin film of the single-component ferroelectric ...

We construct maximal supergravity in five-dimensions by ‘oxidizing’ the four-dimensional = 8 theory. The relevant symmetries, the unitary symplectic group USp(8) and the exceptional group E6, are both presented in light-cone ...

A search for electroweak production of a single vectorlike 𝑇 quark in association with a bottom (𝑏) quark in the all-hadronic decay channel is presented. This search uses proton-proton collision data at √𝑠 =13  TeV ...