NIRWAN, NEHA; Itoh, Yuzuru; SINGH, PRATIMA; BANDYOPADHYAY, SUTIRTHA; Vinothkumar, Kutti R.; Amunts, Alexey; KAYARAT, SAIKRISHNAN
(Nature Publishing Group, 2019-07)
The AAA+ GTPase McrB powers DNA cleavage by the endonuclease McrC. The GTPase itself is activated by McrC. The architecture of the GTPase and nuclease complex, and the mechanism of their activation remained unknown. Here, ...