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  • Mechanistic insights into enzymatic catalysis by trehalase from the insect gut endosymbiont Enterobacter cloacae 
    Adhav, Anmol; HARNE, SHRIKANT; Bhide, Amey J.; Giri, Ashok; PANANGHAT, GAYATHRI; Joshi, Rakesh (Wiley, 2019-05)
    Energy metabolism in the diamondback moth Plutella xylostella is facilitated by trehalase, an enzyme which assists in trehalose hydrolysis, from the predominant gut bacterium Enterobacter cloacae. We report the biochemical ...
  • Histidinal-Based Potent Anti-Malarial Agents 
    Meena, Chhuttan L; Hingamire, Tejashri; Gupta, Tanya; DESHMUKH, BHAGYASHREE; KARMODIYA, KRISHANPAL; Joshi, Rakesh; Shanmugam, Dhanasekaran; Sanjayan, Gangadhar J. (Wiley, 2023-05)
    Herein we report the synthesis and evaluation of peptide-histidinal conjugated drug scaffolds, which have the potential to target the hemoglobin-degrading proteases falcipain-2/3 from the human malaria parasite. Scaffolds ...

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