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  • SATB1 dictates expression of multiple genes including IL-5 involved in human T helper cell differentiation 
    Ahlfors, Helena; Limaye, Amita; Elo, Laura L.; Tuomela, Soile; Burute, Mithila; Gottimukkala, Kamalvishnu P.; Notani, Dimple; Rasool, Omid; GALANDE, SANJEEV; Lahesmaa, Riitta (American Society of Hematology, 2010-09)
    Special AT-rich binding protein 1 (SATB1) is a global chromatin organizer and a transcription factor regulated by interleukin-4 (IL-4) during the early T helper 2 (Th2) cell differentiation. Here we show that SATB1 controls ...
  • NF-κB Signaling and IL-4 Signaling Regulate SATB1 Expression via Alternative Promoter Usage During Th2 Differentiation 
    KHARE, SATYAJEET P.; SHETTY, ANKITHA; BIRADAR, RAHUL; PATTA, INDUMATHI; Chen, Zhi Jane; SATHE, AMEYA V.; REDDY, PULI CHANDRAMOULI; Lahesmaa, Riitta; GALANDE, SANJEEV (Frontiers Media S.A., 2019-04)
    SATB1 is a genome organizer protein that is expressed in a lineage specific manner in CD4+ T-cells. SATB1 plays a crucial role in expression of multiple genes throughout the thymic development and peripheral differentiation ...
  • Interactome Networks of FOSL1 and FOSL2 in Human Th17 Cells 
    SHETTY, ANKITHA; Bhosale, Santosh D.; Tripathi, Subhash Kumar; Buchacher, Tanja; Biradar, Rahul; Rasool, Omid; Moulder, Robert; GALANDE, SANJEEV; Lahesmaa, Riitta (American Chemical Society, 2021-09)
    Dysregulated function of Th17 cells has implications in immunodeficiencies and autoimmune disorders. Th17 cell differentiation is orchestrated by a complex network of transcription factors, including several members of the ...

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