NAGARKAR, SANKET; WASNIK, RUCHI; GOVADA, PRAVALLIKA; Cohen, Stephen; SHASHIDHARA, L.S.
(Genetics Society of America, 2020-09)
Promoter proximal pausing (PPP) of RNA polymerase II has emerged as a crucial rate-limiting step in the regulation of gene expression. Regulation of PPP is brought about by complexes 7SK snRNP, P-TEFb (Cdk9/cycT), and the ...