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A convenient route to synthesize N2-(isobutyryl)-9-(carboxymethyl)guanine for aeg-PNA backbone

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dc.contributor.author DATTA, DHRUBAJYOTI en_US
dc.date.accessioned 2022-06-13T04:29:00Z
dc.date.available 2022-06-13T04:29:00Z
dc.date.issued 2020-08 en_US
dc.identifier.citation Nucleosides, Nucleotides & Nucleic Acids, 39(4) , 530-541. en_US
dc.identifier.issn 1525-7770 en_US
dc.identifier.issn 1532-2335 en_US
dc.identifier.uri https://doi.org/10.1080/15257770.2019.1666139 en_US
dc.identifier.uri http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/7029
dc.description.abstract Synthesis of exclusive N2-(isobutyryl)-9-(carboxymethyl)guanine, an important moiety for peptide nucleic acid synthesis has been reported through a high-yielding reaction scheme starting from 6-chloro-2-amino purine. Crystal structures of two intermediates confirmed the formation of N9-regioisomer. This new synthetic route can potentially replace the conventional tedious method with moderate overall yield. en_US
dc.language.iso en en_US
dc.publisher Taylor & Francis en_US
dc.subject Chemistry en_US
dc.subject 2020 en_US
dc.title A convenient route to synthesize N2-(isobutyryl)-9-(carboxymethyl)guanine for aeg-PNA backbone en_US
dc.type Article en_US
dc.contributor.department Dept. of Chemistry en_US
dc.identifier.sourcetitle Nucleosides, Nucleotides & Nucleic Acids en_US
dc.publication.originofpublisher Foreign en_US


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