Assay for Determining Target Engagement in Real-Time in Living Systems

dc.date.accessioned	2023-02-17T05:50:29Z
dc.date.available	2023-02-17T05:50:29Z
dc.date.issued	2022-06	en_US
dc.identifier.uri	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/7611
dc.description.abstract	The present disclosure relates to an assay for determining drug-target engagement in real-time. Specifically, the present disclosure provides a method for determining drug candidate-target interaction in real-time in living systems using Activity-based Reporter Gene Technology - Bioluminescence Resonance Energy Transfer (AbRGT-BRET) based assay. The said assay is useful for High Throughput Screening of compounds to a specific target.	en_US
dc.language.iso	en	en_US
dc.subject	Biology	en_US
dc.subject	Chemistry	en_US
dc.subject	Patent	en_US
dc.title	Assay for Determining Target Engagement in Real-Time in Living Systems	en_US
dc.type	Patent	en_US
dc.publisher.department	Dept. of Biology,	en_US
dc.publisher.department	Dept. of Chemistry	en_US
dc.assignee	Indian Institute of Science Education and Research Pune	en_US
dc.identifier.patentnumber	IN202121011849A	en_US
dc.application.number	IN202121011849A	en_US
dc.application.code
dc.date.application	2021-03	en_US
dc.publication.kindcode	A	en_US
dc.publication.country	IN	en_US
dc.contributor.inventor	BRITTO, SANDANARAJ S.	en_US
dc.contributor.inventor	BATHLA, PUNITA	en_US
dc.contributor.inventor	De, Abhijit	en_US
dc.contributor.inventor	Mujawar, Aaiyas	en_US
dc.application.patentstatus		en_US