Analysis of GRHL3 Expression in the Zebrafish Epidermis Upon Defective Intracellular Transport

dc.contributor.advisor	Sonawane, Mahendra S.	en_US
dc.contributor.author	POFARE, AMEYA	en_US
dc.date.accessioned	2018-04-23T09:05:17Z
dc.date.available	2018-04-23T09:05:17Z
dc.date.issued	2017-04	en_US
dc.identifier.uri	http://dr.iiserpune.ac.in:8080/xmlui/handle/123456789/856
dc.description.abstract	The skin functions as a protective barrier for the body. The epidermis is the outermost layer of the skin and is constantly exposed to wear and tear. Some mutants of zebrafish show balling up of epidermal cells wherein the cells shows accumulation of vesicles. Previous work in the lab has shown increased expression of grainyhead like-3 in balled up cells of myosin Vb mutants (unpublished). Presented work shows more evidence of upregulation of grainyhead like-3 in balled up cells, namely in clint1 morphants and romeharsha mutants. This suggests a strong correlation between the wound healing mechanism of grainyhead like-3 and the recovery of balled up cells.	en_US
dc.language.iso	en	en_US
dc.subject	2018
dc.subject	Biology	en_US
dc.subject	Zebrafish Epidermis	en_US
dc.subject	Defective Intracellular Transport	en_US
dc.title	Analysis of GRHL3 Expression in the Zebrafish Epidermis Upon Defective Intracellular Transport	en_US
dc.type	Thesis	en_US
dc.type.degree	BS-MS	en_US
dc.contributor.department	Dept. of Biology	en_US
dc.contributor.registration	20121042	en_US