Unveiling the catalytic synthesis of macrolactams from nitro-alcohols: a single-catalyst two-step strategy integrating hydrogen auto-transfer and acceptorless dehydrogenation

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dc.contributor.authorNAIR, PADMAVATHY V. K.en_US
dc.contributor.authorSWAMI, GOURISHANKAR B.en_US
dc.contributor.authorGNANAPRAKASAM, BOOPATHYen_US
dc.contributor.departmentDept. of Chemistryen_US
dc.date.accessioned2026-09-24T07:27:26Z
dc.date.issued2026-09en_US
dc.description.abstractMacrolactams are remarkable molecules whose synthesis is considered difficult due to the greater likelihood of entropy-driven side reactions and strain. Herein, we report a Ru-MACHO-catalyzed two-step synthesis of oxa-aza macrolactams from nitro-alcohols combining borrowing hydrogenation and acceptorless dehydrogenation concepts. This protocol is sustainable, step-economic and exhibits broad substrate scope.en_US
dc.identifier.citationChemical Communications, 62(75).en_US
dc.identifier.issn1359-7345en_US
dc.identifier.issn1364-548Xen_US
dc.identifier.sourcetitleChemical Communicationsen_US
dc.identifier.urihttps://doi.org/10.1039/d6cc03714cen_US
dc.identifier.urihttps://dr.iiserpune.ac.in/handle/123456789/11445
dc.language.isoenen_US
dc.publication.originofpublisherForeignen_US
dc.publisherRoyal Society of Chemistryen_US
dc.subjectChemistryen_US
dc.subject2026-SEP-WEEK1en_US
dc.subjectTOC-SEP-2026en_US
dc.subject2026en_US
dc.titleUnveiling the catalytic synthesis of macrolactams from nitro-alcohols: a single-catalyst two-step strategy integrating hydrogen auto-transfer and acceptorless dehydrogenationen_US
dc.typeArticleen_US

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